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HDM Z2 Auto Travel APAP Machine with Z-Breathe™

The Human Design Medical Z2 Auto CPAP Machine is an improved version of the popular Z1 Auto Travel CPAP machine. It’s small enough to fit into the tightest space... VIEW MORE

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The Human Design Medical Z2 Auto CPAP Machine is an improved version of the popular Z1 Auto Travel CPAP machine. It’s small enough to fit into the tightest spaces and is designed to satisfy the needs of almost any traveler. The Z2 Auto is also FAA compliant and can be carried on an airplane and used in-flight.

The Z2 Auto CPAP features waterless humidification that uses the humidity from your breath to provide moisture for your sinuses, mouth, and throat. You’ll also be able to use your preferred mask for treatment— and not have to compromise sleep therapy.

    The Human Design Medical Z2 Auto also has advanced data tracking features. You can view the results of your therapy on a mobile device using the Nitelog App, available for Apple or Android devices. The Z2 also allows for a USB connection to a personal computer, allowing you to download your therapy to any Windows computer.

  • One of the Lightest CPAP Machines Available Today!
  • Auto Start / Auto Stop
  • Waterless Humidification with HME
  • Automatically Adjusts to Correct Pressure
  • Advanced Data Tracking with USB and Bluetooth
  • Z-Breathe Pressure Relief
  • Compatible with Optional PowerShell Battery
  • Whisper-Quiet Z2 Runs at Only 26 Decibels
  • With a new motor 29% quieter than the Z1, the Z2 is designed to minimize the pitch of the motor for optimal comfort. At 26 decibels, the sound the Z2 makes is almost like a whisper, quietly working in the background while you sleep. With the included Q-Tube Muffler, the sound will dampen even further, creating a sleep environment with possibly fewer interruptions.

    Differences from the Z1:
  • 29% Quieter Motor
  • 30-Day Money Back Guarantee
  • FREE Q-Tube to Further Reduce Noise
  • FREE Q-Tube CPAP Muffler Included with Purchase

    The Q-Tube CPAP Muffler is designed to reduce machine, hose, and mask noise by quieting the ambient sound generated by therapy. This is especially helpful for anyone who is sensitive to noise. The Q-Tube muffler is included with a purchase of the Z2, and can also be purchased separately.

    One of the Lightest Travel CPAP Machines on the Market Today

    Weighing in at a mere 10.4 ounces, you can comfortably pick up the Z2 with only one hand. It small enough to fit in almost any bag, and can go almost anywhere. It’s one of the lightest mini CPAP machines on the market today, and it can be carried wherever life’s adventures take you!

    Auto Start / Auto Stop

    To avoid having to reach over to turn on your machine, the Z2 is smart enough to detect changes in your breathing (after putting on your mask) and can automatically start. Similarly, it can tell when you’ve woken up, and it will automatically stop.

    Waterless Humidification System with HME

    If you’re tired of lugging around distilled water every time you travel, you’ll be pleased to know the Human Design Medical Z2 Auto can use moisture from your exhaled breath to keep your nose and throat from drying out. This way, instead of the mess and hassle of using a tank of water, all you need to do is breathe.

    Automatic Pressure Adjustments

    The Z2 measures breathing on a breath-by-breath basis and automatically adjusts to the correct therapy pressure. Unlike CPAP machines requiring a manual changing of pressures, the Z2 automatically adapts to your changing needs, meaning your treatment level will never be too high or too low— and can help reduce trips to the doctor for pressure adjustments.

    Advanced Data Tracking with USB and Bluetooth

    With the Z2 you have the option of viewing your therapy data on your Windows computer using advanced software and the included USB cable. You can also track your therapy on your phone using the Nitelog App for Android and Apple. The Z2 will help you track and follow the success of your treatment. The data from the Nitelog App can also help you spot problems early, and it will give you a starting point when talking with your doctor.

    Z-Breathe Pressure Relief Helps Make it Easier to Exhale

    To make it easier to exhale, the Z2 Auto features Z-Breathe technology, temporarily reducing the pressure during exhalation. This helps a person have a more normal breathing pattern and makes it more comfortable to use.

  • Z2 device
  • Tube adaptor
  • 4-foot Slim-Style tube
  • Power supply (auto-switching for international travel)
  • Custom USB cable
  • HME (1) good for 5-7 days of use
  • User manual & Get Started guide
  • 1 Filter
  • Q-Tube
  • 2-year warranty



6.3L x 3.5W x 2H

AC (Wall) Power

AC power 100-240V, 50-60Hz (Auto Sensing)

Operating Temperature

5 - 35 degrees Celsius (41 to 95 degrees F)


4-20 cmH2o

Therapy Modes



7.9 oz

Sound Pressure Level

26 dBA or less


2 years

Altitude Adjustment

Automatic Up To 8000 Feet

AC Power Cord Length

10 Feet 4 Inches

Insurance Code(s)